Welcome to the documentation of PyTFA !

TFA is a method that builds on FBA to improve its solution space. Specifically, it includes thermodynamics and explicit formulation of Gibbs energies and metabolite concentrations, which enables straightforward integration of metabolite concentration measurements.

If you use our work, please cite us 1 !


Salvy, P., Fengos, G., Ataman, M., Pathier, T., Soh, K. C., & Hatzimanikatis, V. (2018). pyTFA and matTFA: a Python package and a Matlab toolbox for Thermodynamics-based Flux Analysis. Bioinformatics, 35(1), 167-169.

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